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A TcPO₂ value of ≥40 mmHg near the wound indicates adequate tissue oxygenation for healing. Values below 20 mmHg suggest poor prognosis, while 20–30 mmHg is borderline. HBO may help borderline cases if oxygen challenge improves readings.

Heating dilates capillaries, allowing better diffusion of oxygen through the skin, providing accurate TcPO₂ readings. Without heating, results underestimate tissue oxygenation.

Claustrophobia is not an absolute contraindication. Patients may tolerate treatment with pre-session education, reassurance, or anxiolytics. Faster pressurization is unsafe, and synthetic clothing is prohibited.

Heating the electrode increases skin perfusion by dilating capillaries, allowing oxygen to diffuse more effectively and providing an accurate measurement of tissue oxygenation. Without heating, readings may underestimate oxygen delivery. The goal is to mimic maximal perfusion potential and assess whether wound healing is feasible. This technical step is essential in ensuring reliability of TCOM values for patient evaluation.

Carbon dioxide scrubbers remove exhaled CO₂, which can accumulate in enclosed environments, leading to hypercapnia, headache, and altered consciousness. In multiplace chambers, scrubbers work alongside ventilation to maintain safe gas composition. Without scrubbers, CO₂ buildup could compromise patient safety even if oxygen delivery is adequate. CHTs must regularly monitor and service scrubbers to ensure chamber safety.