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If a conscious patient becomes hypoglycemic during HBO, the first response is to provide oral glucose (juice, glucose gel). If unconscious, IV dextrose may be given once the patient is stabilized, typically without immediate decompression unless life-threatening instability exists. Decompression may compromise therapeutic benefit and is not the first action. CHTs must routinely check glucose levels in diabetic patients and be prepared for prompt hypoglycemia management.

The Undersea and Hyperbaric Medical Society (UHMS) publishes peer-reviewed guidelines on approved HBO indications and best practices. FDA regulates devices, NFPA governs fire safety, and OSHA enforces workplace safety standards, but UHMS defines evidence-based medical use.

Radiation cystitis and proctitis are UHMS-approved indications. HBO stimulates angiogenesis and restores vascularity to irradiated tissues, improving healing. Hair loss, nausea, and leukopenia are not indications.

Dalton’s Law states that the total pressure of a gas mixture equals the sum of the partial pressures of its components. In hyperbaric environments, as the ambient pressure rises, the partial pressures of oxygen, nitrogen, and other gases increase proportionally. This principle is central to oxygen toxicity, where increased oxygen partial pressure (PO₂) in tissues can exceed safe thresholds, resulting in seizures or pulmonary injury. CHTs must monitor oxygen exposure limits to prevent central nervous system (CNS) or pulmonary oxygen toxicity, applying oxygen dose calculations and scheduling air breaks.

Staged decompression provides time for nitrogen to leave tissues safely, avoiding bubble formation that leads to decompression sickness. Without staged ascent, rapid decompression causes dangerous gas emboli.