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Family history of MI, coronary revascularization, or sudden death before age 55 (male first-degree relative) or 65 (female) is a positive risk factor. High HDL ≥60 mg/dL is a negative risk factor. Age 42 woman is below threshold (≥55). Non-smoker removes risk.

Muscular endurance benefits from lighter loads (<50% 1RM), higher reps (15–25+), and shorter rests. Strength/hypertrophy require heavier loads. ACSM notes that endurance improves local fatigue resistance, beneficial for daily tasks and occupational demands.