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These are signs of an acute hemolytic transfusion reaction, which is life-threatening. The nurse must immediately stop the transfusion, maintain IV access with normal saline, and notify the provider. Option A delays critical action. Option B follows after the transfusion is stopped. Option D may be part of supportive care but is not the first step. This falls under Physiological Integrity—Reduction of Risk Potential. NCLEX prioritization focuses on safety and immediate response to life-threatening events. Nurses must know transfusion protocols, monitor closely, and act quickly to prevent complications.

The priority is suicide risk assessment by asking directly about suicidal intent and plan. This ensures safety. Options B and C may help later. Option D provides false reassurance. This falls under Psychosocial Integrity—Crisis Intervention. NCLEX emphasizes client safety as the highest priority in cases of suicidal ideation.

Colon cancer screening guidelines (USPSTF/ACS) recommend average-risk adults begin screening at age 50. Options include annual fecal occult blood testing, flexible sigmoidoscopy every 5 years, or colonoscopy every 10 years. Option A is incorrect—colonoscopy is every 10 years, not 5, unless high-risk. Option C has the wrong interval. Option D is incorrect because screening is recommended before symptoms develop. This content falls under Health Promotion and Maintenance, which includes disease prevention, screening, and early detection. NCLEX-RN emphasizes client teaching that supports healthy lifestyle choices and adherence to preventive care. Nurses play a critical role in ensuring clients understand guidelines and promoting adherence to reduce morbidity and mortality.

High-flow oxygen may suppress the hypoxic drive in COPD clients, leading to CO₂ retention. Oxygen should be administered at 1–2 L/min. Option A is unsafe. Option C worsens fatigue. Option D impairs breathing. This falls under Physiological Integrity—Basic Care and Comfort. NCLEX emphasizes safe oxygen therapy tailored to chronic conditions.

High oxygen flow can suppress hypoxic drive in COPD clients, leading to CO₂ retention. The priority is to reduce oxygen to 1–2 L/min. Option A worsens the problem. Option C impairs breathing. Option D is supportive but not priority. This falls under Physiological Integrity—Basic Care and Comfort/Respiratory Management. NCLEX emphasizes safe oxygen administration tailored to chronic conditions.